About us
At O'Keeffe Health Care, we believe in providing affordable, timely, and high-quality family nurse practitioner services in Floresville. Our patients' experiences are at the heart of what we do. Read on to discover what they appreciate most about our care, helping us reduce health disparities and improve health equity in our community.

"I thought all of the five star reviews were a little fishy. Let me tell you, it has been 22 years and 10 months since I found a doctor that I trusted. She was honest with me and explained what other doctors would not. I even have a follow-up that I plan on attending. That's a first. Thank you for being awesome! Casey Scott, Local Guide "
"What a great experience! On a personal level! One on one expertise! Very compassionate and thorough! Unbelievable desire to see treatment through to completion! Thanks O’Keeffe Healthcare!!! Mike Mckenzie
"You can tell they really care about their patients and know what they are doing! Thank you for helping me out." Wooques
"Absolutely love Melinda!
If you’re looking for a down to earth, honest and helpful provider, you will not find better!" B. Bridges
"Recommend to me by my close friend. Going from miltary care, to VA care, it was difficult to navigate private health care, but O'Keeffe Heath Care has made it easy and I finally feel heard and on the right track to better health." Jennifer Tapia
"Melinda is amazing! She truly cares about her patients.When I leave her office I feel like all my needs are met and I'm informed and up to date on my health care. Angie Anderson-Harbin, Local Guide "
"has a calm demeanor and is very patient and reassuring. Dalton Cruz
"Best Health Care Provider" Isabella Ruiz
"Every time I visit the office of O'Keeffe Health Care, I'm greeted with friendly faces and great service. I know I am in good hands with Mrs Melinda Lee O'Keeffe. She's very professional and takes her time to listen to my concerns. I highly recommend her." Susanne V
I love NP O’Keefe, she really listens to your health concerns, takes her time, and addresses all your questions and needs. Definitely recommend her!" Adrianna C.
"O'Keefe is simply amazing!! Down to earth and she actually listens and most importantly explains everything....I will never see anyone else but her!!" Liz Cano
"I'm a new patient and I can honestly say favorite place she's such a great doctor you can tell she understands and keeps it real" Abbieewonder Land, Local Guide
"Absolutely one of the best around! We have recently started seeing her and she's caught things years of doctors visits have missed." Chrystal Nunya
"Melinda you are the bomb you rock every single time!!! I'm super excited about this Dr. One thing at a time with the patients help she will help fix you. Stay awesome ladies!!!" Geri Trevino
"They were a God send to me. Very nice and caring <3" Catherine Shaffer
"Best in the area. Legitimately listens and addresses my concerns. Her husband is amazing as well. Got a toe nail removed relatively pain free. I recommend to all my friends." Nicholas Cooper
"Great personalized attention and follow up. I couldn"t ask for a better healthcare provider!" EL

"The best primary care that I know. She's professional, personable, caring, knowledgeable, and have a great sense of humor."
Isabella, Patient
Experience O'Keeffe Health Care
Discover the difference personalized, compassionate care can make. Join the many patients who appreciate our commitment to your health and well-being. Contact us today to book your appointment and experience healthcare that truly listens.